Team Leader
Labs & Technologies
Supramolecular Structural Biology Team
Be pioneering.
* Due to the reorganization starting as new centers in April 2018, this laboratory is now belong to the Center for Biosystems Dynamics Research. As for the latest information, please see the following URL below.
> The webpage of Laboratory for Transcription Structural Biology, Center for Biosystems Dynamics Research
Team Leader
Shun-ichi Sekine
1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045 JAPAN (W219)
Research Area
We plan to conduct structural biology studies to unravel action mechanisms of cellular macromolecular systems comprising DNAs, RNAs, and proteins, typified by various complexes of RNA polymerases bound with nucleic acids and transcription factors. To this end, we will develop a technology platform for the supramolecular structure analysis, with novel methods for the preparation of biologically significant macromolecular complexes consisting of a number of large components and for the structure analysis by taking advantage of SPring-8/SACLA and other spectroscopic methods.