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[Feb.8-12] Karolinska Institutet - RIKEN joint doctoral course 2016 "Non-coding RNA as epigenetic regulators: methods, omics technologies and applications in medicine"


February 8th to February 12th, 2016


ca. 9:00 - 18:00


* This image courtesy of Matthias Hörtenhuber

[Summary ] 

A joint international doctoral course on the subject Non-coding RNA as epigenetic regulators: methods, omics technologies and applications in medicine between the RIKEN Center for Life Science Technologies (CLST) and Karolinska Institutet Department of Cell and Molecular Biology (Sweden) will be held from February 8th to 12th at the Karolinska Institutet in Stockholm.

The main purpose of the course is to give doctoral students the possibility to learn about molecular biology from cutting-edge researchers from leading international research institutes. Doctoral students in biology or biology-related areas currently studying in graduate schools either in Sweden or Japan can participate. The course will be held in an international environment with English as course language. This way, students can experience the atmosphere of the world-wide research community and make valuable contacts for their future research career. 

[Participation ] 

The application deadline has already passed.

Doctoral students (medical sciences, biology or related fields) currently enrolled in universities in Japan. Doctoral students enrolled at Universities outside Japan but working in Japanese research institutes can apply and are asked to clarify the details of their multiple affiliations in the application (what is the main location of their work? what is the nature of the association with the Japanese institute? etc.). The screening process for students from Swedish universities is already completed.

[Course content ] 

Non-coding RNA mediated epigenetic regulation in non-disease cases and dysregulation in diseases at individual locus level as well as on genome-wide level including long non-coding RNA, expressed transposons, miRNA, piwi-interacting RNA, and enhancer RNA. Understanding development and disease principles through epigenetic technologies.

After the completed course, the participants will be able to describe the basic methods and mechanisms underlying non-coding RNA mediated epigenetic regulation in non-disease cases and compare and relate these to dysregulation in diseases. The participants will be able to describe and critically evaluate the weaknesses and strengths of the different methods and technologies used in genome-wide epigenomic regulation studies.

See also Karolinska Institutet web-site:

[Lecturers (Alphabetic Order)] 

Alessandro Bonetti (RIKEN Center for Life Science Technologies)

Piero Carninci  (RIKEN Center for Life Science Technologies)

Gonçalo Castel-Branco (Karolinska Institutet)

Carsten O. Daub (Karolinska Institutet)

Chung-Chau Hon  (RIKEN Center for Life Science Technologies)

Weng-Onn Lui (Karolinska Institutet)

Robert Månsson (Karolinska Institutet)

Matti Nikkola (Karolinska Institutet)

Giovanni Pascarella  (RIKEN Center for Life Science Technologies)

Jay Shin  (RIKEN Center for Life Science Technologies)

Takahiro Suzuki  (RIKEN Center for Life Science Technologies)

[Course examination ] 

The students will be examined for knowledge and skills, individually based on the active participation in discussions and group-wise with seminar presentations.

The students are examined with both group-wise and individual presentations in English. The students will work in small groups of 2-3 students. Each group will receive a scientific question related to the course topic on the first day of the course. Students are welcome to propose such a question for their own group. The content has to be related to the course topic. The scientific question will be answered and discussed by the students on the last day of the course during the course evaluation. Each group will be asked to make an oral presentation of the results and each student will present part of the results. The course lecturers will evaluate the performance of each of the students individually. Based on each students performance during the examination, it will be determined if the student pass the examination or not.

Students who successfully pass the examination will receive official certificates of completion from Karolinska Institutet. Special requirements for certificates from the students’ university can be considered. Please contact the course administration before the course if any such requirements exist.

[Course directors ] 

Dr. Carsten O. Daub, RIKEN Center for Life Science Technologies and Karolinska Institutet;

Dr. Piero Carninci, RIKEN Center for Life Science Technologies

CLST was reorganized into three centers according to the RIKEN 4th Medium-Term Plan from April 1, 2018.