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Program | Reception

Program

9:30

Opening Remark
Yasuyoshi Watanabe, RIKEN CLST director

 
Chair: Kazuhiko Tanzawa, RIKEN CLST

9:40


Academic Drug Discovery Centra - Cultural Bridges Over The Valley of Death?
Per Arvidsson, Karolinska Institutet

10:10


A Private-Public Open Source Partnership for Target Definition and Validation
Michael Sundstrom, Karolinska Institutet

10:40


Structure-based development of epigenetics research tools
Takashi Umehara, RIKEN CLST

11:05

Coffee Break

 
Chair: Carsten Daub, Karolinska Institutet / RIKEN CLST

11:25


Karolinska Institutet infrastructure in Protein Structure and Drug Discovery
Karin Dahlman-Wright, Karolinska Institutet

11:55


NMR facility and protein RNA projects
Toshio Yamazaki, RIKEN CLST

12:20


Analysis of drug selectivity profile in their relevant cellular contexts by CETSA-MS
Janne Lehtiö, Karolinska Institutet

12:50
Lunch

 
Chair: Kam Zhang, RIKEN CLST

14:00


Two steps forward, one step back: Successes and Failures in Structure-based Discovery of GPCR ligands
Jens Carlsson, Stockholm University

14:30


Optimization of X-ray complex structures and binding affinity prediction by FMO
Teruki Honma, RIKEN CLST

14:55


Tuning the allosteric modulation of ion channels through computational design
Erik Lindahl, Stockholm University

15:25
Coffee Break


 
Chair: Mikako Shirouzu, RIKEN CLST

15:45


Structural biology on membrane proteins and X-ray free electron laser
So Iwata, RIKEN SPring-8 Center / Kyoto University / Imperial College UK

16:15


Establishing the molecular mechanisms of solute-carrier (SLC) transporters: from snapshots to movies
David Drew, Stockholm University

16:45


Elucidate functional structure of membrane proteins in lipid environment by electron cryo-microscopy single particle analysis
Hideki Shigematsu, RIKEN CLST

17:10


CETSA as a new strategy to understand efficacy, adverse effects and resistance development of anticancer drugs
Pär Nordlund, Karolinska Institutet

This lecture has been canceled.

17:40

Closing Remark
Hiroshi Matsumoto, RIKEN president

18:10

Reception

Reception

We would like to have a reception after the symposium.
This reception, also open for public, is arranged for further discussion, and your participation is very much welcome.
All the speakers will attend.

Starting Time: 18:10-
Fee: 3,000 JPY

Please register your participation through the Symposium Registration Page.