RIKEN Center for Life Science Technologies


  • Research

    Latest publications from CLST.
  • News

    Awards, agreements, and other news.
  • Events

    Upcoming and past events including seminars, symposiums, open days.

For Public

To let you know about our research, this area contains 4 types of information about CLST; “Article”, “Videos”, “Event” and “Study”.
At “Article”, you can read articles on interviews and lectures, and you can enjoy the videos about CLST at “Videos”. If you want to meet and talk directly with the researcher, “Visit” give you some information of such events. You can find more difficult contents to know about our research deeply at “Study”.
  • Article
  • Event
  • Videos
  • Study

About CLST


Knowledge and technology to deepen our understanding of the human being

At the RIKEN Center for Life Science Technologies (CLST), we are working to understand various phenomena of life,including human life, with the aim to develop technologies that can provide medical solutions geared to individuals.


We have two core purposes. One is to develop key technologies that can enable breakthroughs in medical and pharmaceutical applications and bring innovation to our lives. The other is to conduct groundbreaking research and development for the next-generation of life sciences. CLST aims to promote life innovation focusing on three areas of research.

What does it mean to be "healthy"? At first glance this seems like an easy question, but it is not so easy to answer in reality.
What is the secret to achieving a healthy life? We believe that this question can only be answered with new knowledge and
new applied technologies. We are working to elucidate the dynamic behavior of molecules and to learn how to manipulate
them inside the human body. We believe these are keys for the future of drug discovery, diagnosis and medicine.

Create a New Paradigm in the Life Sciences


our mission

We are developing technologies to measure and analyze the entire range of molecules functioning in our body at three levels—the atom, the cell and the individual. To understand their real functions in the living body over time, we use a dynamic-comprehensive approach rather than a static and target-oriented approach.


A unique research and development structure


To elucidate the dynamics of functional molecules in the human body, we need to develop new technologies with specifically human targets. The knowledge derived from these new technologies will be translated into innovations in the life sciences through our unique research and development structure which covers the three different levels of atoms, cells and the body.



Toward personalized medicine

our vision

Even if we are genetically prone to a disease or have some poor lifestyle habits, the molecules working in our bodies do their best to keep us in a healthy state. However, there are limits to how far they can cope, depending on the individual, as the level of molecular activity differs from person to person. We are looking for ways to prevent diseases and to initiate treatment before the onset of disease by regulating molecular function.


Yasuyoshi Watanabe Director, CLST

Our center’s mission is to explore the future potential of next-generation life sciences and contribute to the ultimate goal of the life sciences, which is to allow us to live long healthy and active lives and thus realize a human society where people can feel at ease. Since the late 20 century, we have witnessed amazing progress in the life sciences, but there remain many discoveries to be made. We have yet to reach the stage where we can even fully describe the various function of the human body in our own language. However, humans have developed long-lived and comfortable societies by learning from nature, unlocking the secrets of living things and organisms, and adopting their systems even while feeling astonishment at the ingenuity of nature.In order to make a leap to next-generation life sciences, CLST will carry out research ranging from microorganisms and animals to humans, from elements to the integration of elements, and from stop-motion photography to the dynamic and temporal observations of video. Under our new concept of Live Science, CLST will transmit information as a scientific base supporting Japan and the world. We look forward to working with you.

Yasuyoshi Watanabe
Center for Life Science Technologies

The CLST logo is composed of a helix made up of circle that represent atoms and biomolecules such as nucleic acids and protein. The green color stands for life. The logo expresses how, thorough CLST, RIKEN is developing new technologies for life science research and opening up a new era in the life sciences.


RIKEN Center for Life Science Technologies Pamphlet


Last update:April, 2015




Yasuyoshi Watanabe


Mikako Shirouzu
Deputy Director

副センター長CARNINCI Piero

Piero Carninci
Deputy Director

CLST was reorganized into three centers according to the RIKEN 4th Medium-Term Plan from April 1, 2018. For the latest information of each groups, please visit the following three centers websites.

> Center for Integrative Medical Sciences [http://www.ims.riken.jp/en/]

Devision of Genomic Technologies now belongs here.

> Center for Biosystems Dynamics Research [http://www.bdr.riken.jp/en/]

Division of Bio-Function Dynamics Imaging, and some groups of Division of Structural and Synthesis Biology now belong here.

> RIKEN SPring-8 Center [http://rsc.riken.jp/eng/index.html]

Some NMR groups from Division of Structural and Synthesis Biology now belong here.