RIKEN Center for Life Science Technologies


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    Latest publications from CLST.
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For Public

To let you know about our research, this area contains 4 types of information about CLST; “Article”, “Videos”, “Event” and “Study”.
At “Article”, you can read articles on interviews and lectures, and you can enjoy the videos about CLST at “Videos”. If you want to meet and talk directly with the researcher, “Visit” give you some information of such events. You can find more difficult contents to know about our research deeply at “Study”.
  • Article
  • Event
  • Videos
  • Study

Labs & Technologies

Division of Structural and Synthetic Biology

We plan to develop novel methods for the structural analysis of biomolecules and establish technologies to rationally design "control molecules".

It is necessary to know the structures of macromolecular or supramolecular complexes consisting of proteins and nucleic acids in clarifying the dynamic functions of biological systems. For this purpose, we will establish superb technology platform by integrating next-generation technologies using SPring-8 (synchrotron radiation)/SACLA (X-ray Free-Electron Laser), and advanced NMR spectrometer and spectroscopy techniques. We also act as the core facility for an NMR platform network connecting major domestic NMR centers.

We will develop middle- and high-molecular weight molecules (proteins and nucleic acids), as well as chemical compounds, that can be used to modulate cell and cellular activities. For this purpose, we plan to exploit not only proprietary technologies, such as expanded genetic codes, but also the state-of-the-art computing resources, such as K-computer, of RIKEN. We intend to contribute to drug discovery and the advancement of medical technologies through combining the activities of the group and division. 


Division Director
Mikako Shirouzu  Ph.D.


CLST was reorganized into three centers according to the RIKEN 4th Medium-Term Plan from April 1, 2018. For the latest information of Division of Structural and Synthetic Biology, please visit the following websites.

> Center for Biosystems Dynamics Research [http://www.bdr.riken.jp/en/research/index.html]

Structural Biology Group and Bio-functional Molecule Development Group now belong here.

> RIKEN SPring-8 Center [http://rsc.riken.jp/eng/index.html]

Some NMR groups from DSSB now belong here.