Unit Leader

* Due to the reorganization starting as new centers in April 2018, this laboratory is now belong to the Center for Integrative Medical Sciences. As for the latest information, please see the following URL below.
> The webpage of Laboratory for Applied Computational Genomics, Center for Integrative Medical Sciences
Unit Leader
Michiel de Hoon
1-7-22 Suehiro-cho, Tsurumi-ku,Yokohama City, Kanagawa,230-0045, Japan
tel: 045-503-9111
Genome-wide transcriptome studies such as FANTOM and ENCODE have shown that genomic loci generate a wide variety of transcript isoforms, many of which do not code for proteins. Though in most cases the specific biological function of such non-coding RNAs is unknown, their cell-type specific expression patterns suggest that they play essential roles in establishing cell type identity. The unit will develop and apply novel methodologies to analyze genome-wide data generated using next-generation sequencers for the purpose of categorizing and functionally understanding RNA molecules, their role in biological networks, as well as the relation between the function and the 3D structure of the non-coding RNA.
CLST was reorganized into three centers according to the RIKEN 4th Medium-Term Plan from April 1, 2018. For the latest information of Genomics Algorithms Development Unit, please visit the following websites.
> The webpage of Laboratory for Applied Computational Genomics, Center for Integrative Medical Sciences [http://www.ims.riken.jp/labo/62/index.html]
> If you continue to browse this site, click here.