RIKEN Center for Life Science Technologies


  • Research

    Latest publications from CLST.
  • News

    Awards, agreements, and other news.
  • Events

    Upcoming and past events including seminars, symposiums, open days.

For Public

To let you know about our research, this area contains 4 types of information about CLST; “Article”, “Videos”, “Event” and “Study”.
At “Article”, you can read articles on interviews and lectures, and you can enjoy the videos about CLST at “Videos”. If you want to meet and talk directly with the researcher, “Visit” give you some information of such events. You can find more difficult contents to know about our research deeply at “Study”.
  • Article
  • Event
  • Videos
  • Study


  • Forcing a molecular light switch

    A chance observation led to RIKEN researchers discovering an organic compound whose fluorescence wavelength varies greatly when it is subjected to a mechanical force1. This property makes it an attractive material for various applications in security as well as medical imaging and therapy.
  • Tracing the spread of vitamin B1

    RIKEN was, from its earliest days, a pioneer in vitamin research. A century later, RIKEN is still on the leading edge of vitamin research. In May, researchers from the RIKEN Center for Life Science Technologies (CLST) announced the development of a technique to "tag" vitamin B1 and a thiamine analogue, fursultiamine, with a short-lived radioisotope of carbon, 11C (which has a half-life of 20.4 min), allowing the use of PET imaging to determine how the vitamin spreads through the body following injection.
  • A dictionary of the language of cells

    In their struggle to survive and prosper, multicellular organisms rely on a complex network of communication between cells, which in humans are believed to number about 40 trillion. Now, in a study published in Nature Communications, a research group led by scientists from the RIKEN Center for Life Science Technologies (CLST) has published an overall map of how the cells in the human body communicate by systematically analyzing the relationship between ligands—substances such as insulin and interferon that embody messages between cells, and receptors—the proteins on cell surfaces that receive these messages when bound by the ligands.
  • Engineering the world’s smallest nanocrystal

    Now, in research published in Angewandte Chemie International Edition, scientists from the group of Kam Zhang at the RIKEN Center for Life Science Technologies (CLST) and the group of Jeremy Tame at Yokohama City University in Japan have used an artificially designed protein to create a cadmium chloride nanocrystal—the smallest crystal reported so far, made up of just 19 atoms—sandwiched between two copies of the protein.
  • World’s Highest Magnetic Field* (1,020MHz) NMR developed

    The research team of NIMS, RIKEN, Kobe Steel and JEOL RESONANCE successfully developed the NMR system equipped with world’s highest magnetic field, 1,020 MHz, supported by the JST-SENTAN program “Development of Systems and Technology for Advanced Measurement and Analysis”. This research result was published in Journal of Magnetic Resonance on 15 May 2015 (Kenjiro Hashi, Shinobu Ohki, Shinji Matsumoto, Gen Nishijima, Atsushi Goto, Kenzo Deguchi, Kazuhiko Yamada, Takashi Noguchi, Shuji Sakai, Masato Takahashi, Yoshinori Yanagisawa, Seiya Iguchi, Toshio Yamazaki, Hideaki Maeda, Ryoji Tanaka, Takahiro Nemoto, Hiroto Suematsu, Takashi Miki, Kazuyoshi Saito and Tadashi Shimizu, Title:”Achievement of 1,020 MHz NMR”, DOI:10.1016/j.jmr.2015.04.009).
  • Seeking a Unit Leader [DDI-1501]

    The Drug Discovery Imaging Platform Unit is advancing in vivo pharmacokinetic research of marmosets (monkeys), mice and humans by utilizing molecular imaging technology focused on positron emission tomography (PET). Labeling technologies for molecular imaging probes guarantee in vivo observation time and improve tracing after metabolic breakdown. Also, with a view to clinical studies of microdoses, we aim to build new drug discovery processes, developing labeling and probes for drug candidate compounds, as well as utilizing mice-to-human streamlined molecular imaging techniques.
  • [Nov.8th - Nov.11th] The 29th International Mammalian Genome Conference

    The 29th International Mammalian Genome Conference will be held from November 8th to November 11th at the Yokohama Port Opening Memorial Hall, a historic building designated as Important Cultural Property of Japan by the Japanese Government, and will start with a Student Symposium on Sunday, November 8th, followed by the main conference on November 9th to 11th.
  • Seeking a Team Leader [GIAT-1501]

    The Genome Information Analysis Team studies transcriptional networks and develops innovative analysis technologies based on next generation sequencing data. Currently there are several bioinformaticians and a wet technician in the team and research projects include cancer biomarker discovery, transcriptional network models, time-series analysis, development of new bioinformatics tools such as the ZENBU Genome Browser and the over-arching bioinformatics analysis for the FANTOM projects. There is potential for the new leader to build a research portfolio based on analysis of large scale Next Generation Sequencing (NGS) data, in particular coupled to new technologies, which we develop in the Division, to broadly understand biological function.
  • iPS and embryonic stem cells: not quite the same

    In research recently published in Cell Cycle, a group of scientists led by Piero Carninci of the RIKEN Center for Life Science Technologies analyzed the genes that are transcribed in the nuclei of embryonic stem cells and iPS cells—a type of cell that is reprogrammed from normal somatic cells with the intention to have them act like stem cells—and discovered that there are significant differences between the two.
  • Remapping the damaged brain

    Scientists at CLST, along with researchers from the AIST have identified a time-dependent interplay between two brain regions that contributes to the recovery of motor function after focal brain damage, such as a stroke. Published in the Journal of Neuroscience, the research shows that when motor functions are remapped through rehabilitative training, brain regions relatively distant from a lesion are recruited during the initial stages and functional connections with regions near the lesion are strengthened during the latter stages.
  • Diane Delobel awarded at JFR'14

    On November 21, Diane Delobel (research associate of Genetic Diagnosis Technology Unit) was presented the Best poster award of JFR'14 (Journée Francophone de la Recherche 2014) .
  • Collaboration in super high-field magnetic research

    On August 8, we signed an agreement with the National High Magnetic Field Laboratory (NHMFL) in the United States to conduct collaborative research in the area of super high-field magnets.


For Public

RIKEN Kobe Campus Open House

Open House 2015 at RIKEN Kobe Campus will be held on this fall!

Day : Oct. 24, 2015
Place : RIKEN Kobe Campus